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| May 31 (approx.) | ||
|---|---|---|
 NOVA | vere joins. | |
 ALPH | Energy, Jaano, Melteck, and NanZ leave. | |
| May 31 | ||
 AA | Apexcitys, MRuiz, Risky, and TTinyy join. | |
| May 30 | ||
 VIT | Randomm joins. | |
| May 29 | ||
 AW0 | Abuzah, Breszy, Chaaxter, Cobra, and Eddy (Coach) join. | |
 SSY | Warking (Manager) leaves. | |
 LAG Enterprises   Shady Kings in the CDC North America 2022 Cup #11. | ||
 EMG Esports  BSC eSports Team in the CDC Latin America 2022 Cup #11. | ||
 RØKKR Academy  Ultra Academy EU in the CDC Europe 2022 Cup #11. | ||
 VOID Orgless AP in the CDC Asia Pacific 2022 Cup #11. | ||
GM1 |  Omega Esports  Blacklist Ultimate in the Garena Masters 2022 Season 2. | |
| May 28 | ||
| SSY | Eddy (Coach) leaves. | |
EMG Esports  Masters Ecuador in the Ascendance League 2022 Championship. | ||
| May 27 | ||
 LRW | KaTaNi joins. Hate leaves. | |
| May 26 | ||
 HvK | Beehzy, FA5TBALLA, Holler, and ProFeeZy join. | |
| SSY | Cobra, D3L1V3R, Depaa, and Nadox leave. | |
 BTG | FarMa, PaceR, Phenom, and Rixsrr join. | |
 LAT | ShAnE (Assistant Coach) joins. | |
| May 25 | ||
| Ultra Academy NA Shady Kings in the CDC North America 2022 Elite Stage 3 Playoffs. | ||
Ultra Academy EU  AYM Esports in the CDC Europe 2022 Elite Stage 3 Playoffs. | ||
 F/A | Dqvee comes out of retirement. | |
| May 24 | ||
 DTO | Team signs roster of  Trash Bros. Hollow, Jintroid, Mock, and Venom join. | |
 TB | Roster is signed by  Destroy The Odds. Hollow, Jintroid, Mock, Venom, Veohz (Head Coach), and Sharp (Analyst) leave. | |
 SK | Team signs roster of  WhateverItTakes. 2ReaL, Brack, MajorManiak, Neptune, Veohz (Head Coach), and Sharp (Analyst) join. | |
 WIT | Roster is signed by Shady Kings. 2ReaL, Brack, MajorManiak, Neptune, and BrianViiox (Coach) leave. | |
| May 21 | ||
 3KG | Proto joins. | |
| May 20 (approx.) | ||
 VOID | Khizma joins. Middoh leaves. | |
| May 20 | ||
| 3KG | Volants leaves. | |
| May 19 | ||
 D1 | Aaron, Ruper, Thresh, and Traixx join. | |
 SMOG | Ruper and Thresh leave. | |
| May 18 | ||
 WaR | Synical (Analyst) joins. | |
| May 17 | ||
| LRW | Wyggzz (Coach) joins. | |
 sX | Radial and Quids (Coach) join. | |
| 3KG | Gunsiii joins. Whiz leaves. | |
| sX | Gunsiii and Wyggzz (Coach) leave. | |
| May 16 | ||
 LAG | Gunless moves to starting roster. Spart moves to substitute. | |
 AYM | Team signs roster of dos tontos y medio. EriKBooM, JurNii, SupeR, YaKo, Sikotik (Coach), and Guille (Manager) join. | |
| May 15 | ||
 PB | Jazhn joins. Restalling leaves. | |
 Iron Blood Gaming WhateverItTakes in the CDC North America 2022 Cup #10. | ||
| Masters Ecuador EMG Esports in the CDC Latin America 2022 Cup #10. | ||
| Ultra Academy EU RØKKR Academy in the CDC Europe 2022 Cup #10. | ||
 Orgless  PointBlank in the CDC Asia Pacific 2022 Cup #10. | ||
| May 14 | ||
| 3KG | Hamza and Wand join. Dak and Gusify leave. | |
 NY | Neptune leaves. | |
| May 13 | ||
 RG | Sehvin (Coach) joins. | |
| RG | Flinched, React, Reloadz, and Shnopsh join. | |
| May 12 | ||
| ALPH | Energy, Jaano, Melteck, and NanZ join. | |
 NXA | Team signs roster of  Mystaken Esports. JonnyW, Runner, Shaun, and Snake join. | |
 MTK | Roster is signed by  Nixuh. JonnyW, Runner, Shaun, and Snake leave. | |
| May 11 | ||
 705 | Classic, Diamondcon, Prestinni, Royalty, and Abas (Coach) join. | |
 INV | Rafi rejoins. | |
 UA.EU | Gismo joins. Rafi leaves. | |
| WIT | MajorManiak joins. | |
 TEX | Prolute joins. General moves to substitute. | |
| WIT | Prolute leaves. | |
 IBG | Team signs roster of  18andcracked. Assault, Exceed, Noysii, Welly, Arian (Coach), and Cheek (Analyst) join. | |
| IBG | Newb (Coach) joins. | |
 18C | Roster is signed by Iron Blood Gaming. Assault, Exceed, Noysii, Welly, Arian (Coach), and Cheek (Analyst) leave. | |
| May 10 | ||
 EMG | Aaron, DJ, Evadde, Lucho, and Panda (Coach) join. | |
| May 9 | ||
 ESG.W | Cryptic, Kyzer, Mind, Ulisses, Atom (Coach), VinnY (Coach), and GBursted (S&D Analyst) join. | |
 RØK.A | Sukry joins. | |
 SB | Sukry leaves. | |
| May 8 (approx.) | ||
| VOID | Rhein and Sponsord join. JamesJHR and ManOfChicken leave. | |
| May 8 | ||
| HyDra is awarded the Call of Duty League 2022 - Pro-Am Classic MVP. | ||
 New York Subliners  Los Angeles Thieves in the Call of Duty League 2022 - Pro-Am Classic. | ||
 RNG | Fighta, Jazhn, Louqa, and Shockz leave. | |
| May 7 (approx.) | ||
 TRB | Tectonic joins. | |
 NYM | Carlinhos, Rebalo, and Solar join. Awaken, Leon, and Tectonic leave. | |
| May 7 | ||
| Iron Blood Gaming R9 x Above All Else in the Cheetowunga Lord of the Lowtiers Indianapolis 2022. | ||
 Team MM WHATDOUSAY in the Copa de Desafiantes 3. | ||
| WIT | BrianViiox (Coach) joins. | |
| May 6 | ||
 UONA | Desmays joins. | |
| May 5 | ||
| UONA | Aaron joins. | |
| TEX | General moves to starting roster. iLLeY moves to substitute. | |
| TEX | iLLeY moves to starting roster. General moves to substitute. | |
| May 4 | ||
| NY | KiSMET joins. | |
 TN | KiSMET leaves. | |
| May 2 | ||
 LDN | Harry moves to starting roster. Gismo moves to substitute. | |
| UA.EU | Rafi joins. Harry leaves. | |
| INV | Rafi leaves. | |
| May 1 (approx.) | ||
 WOL | King, Nian, Pegg, XQing, and Zai join. | |
| May 1 | ||
| RevelationGG Iron Blood Gaming in the Kinetic Leagues Columbus 2022. | ||
Electrify Steel  Limitless Godz in the AfterDark eSports Kraken Bounty Miami Open 2022. | ||
PointBlank  Mindfreak in the Vertex Esports Vanguard Live Event. | ||